I’m sorry to hear about your niece’s situation, it sounds terrible. I think you’re kind for trying to help her through it
Before offering spell suggestions, I just want to leave a disclaimer that, at least in my experience, spells cast by those at the heart of the issue tend to work best, as opposed to those cast by a third party. This is especially true for things like cord cuttings where an emotional bond is severed. There’s also ethics worth considering, as some people can be very offended when magick is cast on them without their permission. But if you know she wouldn’t mind and you’re set on casting for her, then I have a few suggestions you might use (or send her way)!
Here are few for cutting ties or calling on the divine hand of karma to intervene:
Wishing only the best for you and your niece. Blessed be